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Pharmacists advise to simply cut large pills in half in the future and swallow the halves one at a time Cutting Crestor Pills In Half With a little manual labor -- just snapping down the lid of a pill cutter with your finger -- pill splitting can save quite a lot of money Drugs Drugs that can be usually be split include Lipitor (atorvastatin), Zocor (simvastatin), Crestor It is only recommended that you split accutane long term side effects pregnancy pills in half, not any smaller Crestor is the brand name for rosuvastatin, a prescription drug used to treat high cholesterol levels Crestor is in a class of drugs known as statins, which slow the buildup of plaque in your. Pills that are most commonly split include: Cholesterol lowering drugs, like Crestor, Lipitor, Mevacor, Pravachol and Zocor Some pills may deteriorate after being split, and taking two halves of the same pill consecutively will get you the most even dosing. When Is It Unsafe? User Reviews for Crestor. 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